My Setup

Dell Dimension 9200 (Windows Vista): Main desktop. I use it for all my web dev.

Logitech G15 Keyboard: Probably the best keyboard there is. It has a screen, backlit keys and multimedia controls that don’t feel clunky and out of place. It’s great to type on and, provided you can find one in stock, they’re not ridiculously expensive.
Logitech G9 Mouse: Again, a fantastic product! It fits perfectly in your palm and feels solid. Certainly not for left-handed people though.
Dell 22″ Widescreen Monitor: First off, your next monitor should be a widescreen if it’s not already. Secondly, it should be big. Once you get past 22 inches, though, sizes are sparse and usually carry high prices.

Aptana Studio: I used to use Dreamweaver but I found it unnecessarily bloated and consequently slow. Aptana is a bit more agile and the Community Edition is free.
Adobe Fireworks CS4: Much easier to use than Photoshop just not as powerful.
Adobe Photoshop CS4: The leading image editor.
Mozilla Firefox 3: This is very easily my favourite browser. It’s complete with the Web Developer toolbar and Firebug, among others.
VirtualBox: It’s free so it’s a lot cheaper than buying another computer and a lot safer than dual-booting. In short, I can test a variety of different operating systems quickly to ensure projects work as they should. I find it lighter than VMWare and a little bit easier to use as well.

Creative X-Fi XtremeMusic Sound Card: Good sound card.
Creative Inspire T7900 7.1 Speakers: There’s nothing like being immersed in sound. There are 7 of these speakers and a huge subwoofer. When joined with a Creative X-Fi sound card, the results are phenomenal.
iTunes: iTunes is love/hate software — many people hate it but I quite like it. Sure, it doesn’t have codec support for anything outside Apple confines — FLAC support, for example, is something I wouldn’t mind. But it does, however, support the iPod perfectly and as I have two iPods, that’s a huge advantage. It’s not a bad looking piece of software either, compared to Windows Media Player.
iPod Video 5G: Granted, it was expensive and video playback drained the battery but I love it and it has all my music in one portable device.
iPod Shuffle 1G: For a light journey, nothing beats a Shuffle, in terms of portability and simplicity.

LaCiE 500GB External Drive: Written on the side it says “Designed by F A Porsche”. It’s a great hard drive although it can get fairly warm after a while.